Sexual Dysfunction in Patients with Polycystic Ovary Syndrome: clinical and hormonal correlations

Objective: To investigate the sexual function of patients with Polycystic Ovary Syndrome
(PCOS) including the clinical and hormonal characteristics potentially related to sexual dysfunction, in an endocrinology and gynecology ambulatory.
Methodology: Women in ambulatory accompaniment for PCOS (N=88) were sequentially evaluated by means of the Arizona Sexual Experience Scale (ASEX) and the application of structured diagnostic interview MINI (version 4.4) for the identification of mood disorders. The clinical and laboratorial parameters were examined using the patient's medical records.
Results: The incidence of sexual dysfunction was verified (13.3%) and it was observed that the average ASEX score of (14.4 [SD: 3.7]) was comparable to the population with no medical problems. There is a negative correlation between the scores of ASEX and the levels of total testosterone (-0.360), LH (-0.397) and DHEA-S (-0.723).
Conclusion: As the main factors of preservation of the sexual function in our sample were identified as being, the low average age of the patients in treatment and the hyperandrogenism habitually found as a consequence of the physiopathology of PCOS.

Prevalence of psychiatric disorders in patients with polycystic ovary syndrome

Objective
To investigate the prevalence of psychiatric disorders among women in ambulatory treatment for polycystic ovary syndrome (PCOS) and to correlate its clinical and demographic aspects with mental disorders.
Methodology
Seventy-two patients in ambulatory treatment at the Endocrinal and Gynaecological Institute of the Federal University of Rio de Janeiro were evaluated using Diagnostic and Statistical Manual for Mental Disorders, Fourth Edition criteria by means of MINI (Mini International Neuropsychiatric Interview, version 4.4). Polycystic ovary syndrome was confirmed according to the ultrasonographic criteria of Adams and by clinical parameters.
Results
Forty-one patients (57%) presented at least one psychiatric diagnosis. Among them, the prevalence of mood disorder reached 78%. The most prevalent diagnostics were major depression (26.4%) and bipolar disorder (11.1%).
Conclusion
A high prevalence of mental disorders was observed, especially major depression and bipolar disorder. The data obtained regarding the relationship between PCOS and mood disorders in a Brazilian sample is in accordance with recent research findings in the same area.

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